Although polysorbate 20 plays an important role in the cosmetics industry, it also has various applications in daily life and science.
Used as a wetting agent and flavoring agent in ice drops. It is also used as a peppermint flavoring agent in various foods. Polysorbate 20 is also used as an alternative to SD alcohol in the food industry. polysorbate 20 E432 is used in various foods such as edible oil, cake icing, cake and cake mixtures, cake fillings, salad dressings, cocoa products, chocolate preservatives, chocolate syrups, dairy substitutes, sugar and candy coatings, mineral oils, natural coatings for fruits and vegetables.
The use of polysorbate 20 in cosmetics, is also important in the field of biology and laboratory science. Polysorbate 20 has a wide range of applications. For example, it is used as a cleaning agent for immunoassays in the laboratory, such as protein imprinting and ELISA. Due to its presence, nonspecific antibody contamination can be controlled and prevented from binding. It is used for skin testing for tuberculosis. As a solubilizer for membrane proteins at concentrations of 0.05% to 0.5% v/v, it can lyse mammalian cells and is usually used in combination with other detergents, salts, and additives.
Polysorbate 80 and 20 are both excipients used in aqueous media required to stabilize drug formulations and as emulsifiers when preparing the popular antiarrhythmic drug amiodarone hydrochloride. polysorbate is also present in various vitamin solutions to dissolve water-soluble and fat-soluble vitamins and make different medicinal syrups. In addition, polysorbate is present in a large number of biomedicines such as enzymes (alteplase), immunoglobulin, and monoclonal antibodies, used to prevent surface adsorption and as stabilizers for protein aggregates. Furthermore, for vaccine production, polysorbates 80 and 20 are used as antigens or emulsifiers.
It also has other applications in the pharmaceutical industry, such as preparing influenza vaccines using polysorbate. Each influenza vaccine contains polysorbate 80 at a dose of 2.5 micrograms per dose. polysorbate 20 is also used in the laboratory.
Polysorbate is used to test specific phenotypes of bacterial strains. Some branched bacteria contain lipase. When these species are added to a mixture of polysorbate 20 and phenol red, it causes the solution to change color, so this is used as a test to identify strains or separate strain phenotypes.